| Museum | Location | Telephone | Exhibits |
| African Heritage Museum | Old San Juan | (787) 724-4294 | Artifacts, Photos and History of Slavery Period in Puerto Rico |
| Caparra Ruins Historical Museum and Park | Guaynabo | (787) 781-4795 | Ruins of first settlement by Juan Ponce de León |
| Casa Alonso Museum of Art, History and Culture | Vega Baja | (787) 855-1364 | Depiction of Puerto Rican Life in the 1800’s |
| Casa Cautiño Museum | Guayama | (787) 864-9083 | On U.S. National Register of Historic Places. History of Guayama and Cautiño Family. |
| Casa de la Familia Puertorriqueña Siglo XIX | Old San Juan | (787) 723-1762 | Depiction of Puerto Rican Life in the 19th Century |
| Casa Jesús T. Piñero | Canóvanas | (787) 876-0562 | Home of Puerto Rico’s 1st Govenor |
| Casa Luis Muñoz Rivera | Barranquitas | (787) 857-0230 | Artifacts and History of this Poet, Journalist and Politician a major Puerto Rican Figure. |
| Casa Museo Dr. José Celso Barbosa | Bayamón | (787) 786-8115 | Birthplace of this important Physician, sociologist and political leader. |
| Museo Casa Marcos J. Alegría | Dorado | (787) 796-1433 | Art Exhibition |
| Casa Paoli Museum | Ponce | (787) 840-4115 | Honors the career of the famous Tenor Paoli. |
| Casa Wiechers-Villaronga Museum | Ponce | (787) 843-3363 | Art and History displayed in a 1911 Mansion |
| Castillo Serrallés Museum | Ponce | (787) 259-1774 | Impressive mansion and art collection of the Serrallés Family. |
| Centro Ceremonial Indigena de Caguana | Utuado | (787) 724-4294 | Collection of Artifacts and Archeological items of Puerto Rico’s Indigenous peoples. |
| Fideicomiso Casa Ramón Power y Giralt | Old San Juan | (787) 722-5834 | Historical Artifacts |
| Galeria Nacional | Old San Juan | (787) 725-2670 | Puerto Rico’s National Art Gallery |
| Luis Muñoz Marín Foundation | Trujillo Alto | (787) 755-7979 | History and Artifacts of the Father of Modern Puerto Rico. |
| Museo al Veterano Angel Escribano | San Lorenzo | (787) 736-4427 | Collection of Military Artifacts and History |
| Museo de Arte Contemporáneo | Santurce | (787) 977-4030 | Puerto Rican and Caribbean Art |
| Museo de Arte de Bayamón | Bayamón | (787) 740-6878 | Puerto Rican and International Art |
| Museo de Arte de Caguas | Caguas | (787) 744-8833 | General Art Exhibition |
| Museo de Arte de Ponce | Ponce | (787) 848-0505 | Extensive collection of International Art |
| Museo de Arte de Puerto Rico | Santurce | (787) 977-6277 | World famous collection of Puerto Rican Art |
| Museo de Arte e Historia de Arecibo | Arecibo | (787) 879-4403 | Art, Photographs and History |
| Museo de Arte e Historia de Guánica | Guánica | (787) 821-4343 | History of Guánica |
| Museo de Arte e Historia de Dorado | Dorado | (787) 796-1030 | Artifacts and History of Dorado |
| Museo de la Masacre | Ponce | (787) 844-9722 | History of a Political Event in Puerto Rico |
| Museo de las Américas | Old San Juan | (787) 724-5052 | Art of the Americas |
| Museo de los Próceres | Cabo Rojo | (787) 255-1560 | Historical, Artistic and Cultural Exhibits |
| Museo de los Tres Santos Reyes | Juana Diaz | (787) 837-2199 | The legend of the Three Kings from biblical times. |
| Museo de San Juan | Old San Juan | (787) 723-4317 | Art and History from Old San Juan |
| Museo del Deporte Cagueño | Caguas | (787) 744-8833 | Exhibit of the Sport History of Puerto Rico |
| Museo del Deporte de Guaynabo | Guaynabo | (787) 731-4923 | Exhibit of the Sport History of Puerto Rico |
| Museo del Mundillo de Puerto Rico | Moca | (787) 877-3815 | Dedicated to preserving the history of Bobbin Lace handiwork |
| Museo del Niño | Old San Juan | (787) 722-3791 | Interactive Children’s Museum |
| Museo El Cemí | Jayuya | (787) 828-1241 | Pre-Columbian art and Culture |
| Museo Fe Eleonor Borges | San Lorenzo | (787) 736-1124 | Art and History of San Lorenzo |
| Museo Felisa Rincón de Gautier | Old San Juan | (787) 723-1897 | History, Artifacts and Photographs of the former San Juan Mayor. |
| Museo Fuerte Conde de Mirasol | Vieques | (787) 741-1717 | History, Art and Culture of Vieques |
| Museo Histórico Ramón Rivera Bermúdez | Coamo | (787) 825-1150 | History of Coamo |
| Museo y Centro de Estudios Humanisticos | Gurabo | (787) 743-7979 | Puerto Rican Art |
| Museo Puertorriqueño del Deporte | Salinas | (787) 824-2200 | Puerto Rican Sport History |
| Museo de Vida Silvestre de San Juan | Santurce | (787) 792-9952 | Educational programs, exhibits and resources related to Wildlife |
| Museum of History, Anthropology and Art | Rio Piedras | (787) 763-3939 | University of Puerto Rico Museum |
| Puerto Rican Music Museum | Ponce | (787) 848-7018 | Musical Instrument history and exhibit |
| Pablo Casals Museum | Old San Juan | (787) 723-9185 | Museum dedicated to this famous Puerto Rican Musician |
| Ponce History Museum | Ponce | (787) 844-7071 | 300 years of Ponce’s history |
| Porta Coeli Religious Art Museum | San Germán | (787) 892-5845 | Art and History of Christianity |
